The Curative Activity of Isolated Fraction from Spathodea campanulata Beauv Stem Bark on Rats Exposed to Benzopyrene

Authors

  • Masruri Masruri
  • Mohamad Lutfillah
  • Ady Sumaryanto
  • Rurini Retnowati
  • Aulanni'am Aulanni'am

DOI:

https://doi.org/10.11594/jtls.04.03.01

Abstract

This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA) on rats cancer model exposed with benzopyrene, and the histology of its lung. The secondary metabolite of the stem bark fraction consisted of alkaloids, flavonoids-phenolic, terpenoid and steroid compounds. The isolated fraction contained of these metabolites significantly indicate bioactivity by reducting of malondialdehyde (MDA) level, and also histology appearance of the lung tissue prepared from the benzopyrene-exposed rat indicated a curative activity.

Downloads

Published

2014-12-24

Issue

Vol. 4 No. 3 (2014)

Section

Articles

License

The work has not been published before (except in the form of an abstract or part of a published lecture or thesis) and it is not under consideration for publication elsewhere. When the manuscript is accepted for publication in this journal, the authors agree to automatic transfer of the copyright to the publisher.

Creative Commons License
Journal of Tropical Life Science is licensed under Creative Commons Attribution-NonCommercial 4.0 International License